Related Experiment Video
Updated: Jan 23, 2026
08:53
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
1.6K
Self-administered acupressure for allergic rhinitis: study protocol for a randomized, single-blind, non-specific
Yaqun Liang1, George Binh Lenon1, Angela Wei Hong Yang2
1Discipline of Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, PO Box 71, Bundoora, VIC, 3083, Australia.
Trials
|June 27, 2019
Summary
This study investigates self-administered acupressure as a safe and effective treatment for allergic rhinitis (AR). Results will inform non-pharmacological self-management options for AR sufferers.
Area of Science:
- Integrative and Complementary Medicine
- Clinical Trials
- Allergy and Immunology
Background:
- Allergic rhinitis (AR) is an IgE-mediated inflammatory condition with unsatisfactory conventional treatments.
- Acupuncture is recommended as an optional non-pharmacotherapy for AR.
- Acupressure, a non-invasive acupuncture subtype, offers a low-risk, self-administered option, but requires rigorous evidence.
Purpose of the Study:
- To evaluate the efficacy and safety of self-administered acupressure for managing allergic rhinitis.
- To provide scientific evidence for acupressure as a complementary therapy for AR.
Main Methods:
- A randomized, single-blind, non-specific controlled, two-arm, parallel clinical trial.
- Participants self-administered acupressure on specific or non-specific points twice daily for 4 weeks.
- Outcomes included symptom severity, quality of life (RQLQs), medication use, and adverse events.
Main Results:
- The study is designed to provide scientific evidence on the efficacy and safety of self-administered acupressure for AR management.
- Data analysis will involve chi-square or t-tests to compare outcomes between groups.
Conclusions:
- Findings are expected to support self-administered acupressure as a viable, non-cost, non-invasive self-management strategy for allergic rhinitis.
- This research may contribute to developing accessible self-care methods for AR patients.
Related Concept Videos
02:07Blind Procedures
13.4K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.4K
02:06Allergic Reactions
32.1K
Overview
32.1K
01:11Blinding
3.8K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
3.8K
01:20Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
241
Body:Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to...
241
01:27Allergic Drug Reactions
1.4K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.4K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
415
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
415