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Dimeric opioid antagonists
C W Thornber1, J S Shaw, L Miller
1Department of Chemistry, ICI Pharmaceuticals Division, Macclesfield, Cheshire, UK.
NIDA Research Monograph
|January 1, 1986
Abstract:
Symmetrical and unsymmetrical dimeric pentapeptide opioid antagonists have been prepared and studied on the mouse vas deferens preparation. The findings do not support the hypothesis that such agents bind to dimeric delta-opioid receptors.