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The effect of chronic met-enk on various dopamine systems in the rat
K A Steece1, F A DeLeon-Jones, J M Lee
1Neurobiology Laboratories, West Side VA Hospital, University of Illinois, Chicago.
NIDA Research Monograph
|January 1, 1986
Abstract:
Morphine and enkephalins act preferentially via different receptors, mu and delta, respectively. Chronic administration of morphine or methionine enkephalin results in development of physical dependence. Data from our laboratory suggests that there are some differences in the effect of these two opioids with regards to certain neurochemical systems.