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Computed Tomographic Findings in Unsuspected Aortic Dissection and Adult Polycystic Kidney Disease

H Theodore Harcke1, Wendy S Warren1, Christopher J Gordon1

  • 1Office of the Armed Forces Medical Examiner.

Academic Forensic Pathology
|June 27, 2019
PubMed

Insights

Forensic pathologists and radiologists should recognize the link between adult polycystic kidney disease and aortic dissection. Postmortem imaging reveals characteristic kidney and hemorrhage patterns aiding dissection detection.

Area of Science:

  • Medical Imaging
  • Pathology
  • Radiology

Background:

  • Adult polycystic kidney disease (APKD) is a genetic disorder.
  • Aortic dissection is a life-threatening condition.
  • The association between APKD and aortic dissection is not widely recognized.

Purpose of the Study:

  • To highlight the importance of recognizing the coexistence of APKD and aortic dissection.
  • To illustrate imaging findings in cases with both conditions.
  • To discuss optimal imaging techniques for forensic pathology.

Main Methods:

  • Review of two cases with APKD and aortic dissection.
  • Utilized postmortem computed tomography (CT) prior to autopsy.
  • Analysis of kidney morphology and hemorrhage patterns on CT scans.

Main Results:

  • CT demonstrated characteristic polycystic kidney appearance.
  • Specific hemorrhage patterns correlated with aortic dissection location.
  • Imaging provided crucial clues for diagnosis in postmortem examinations.

Conclusions:

  • Forensic pathologists and radiologists must be aware of this association.
  • Postmortem CT is valuable for identifying APKD and aortic dissection.
  • Recognizing imaging patterns can improve diagnostic accuracy in forensic cases.

Keywords:
Aortic dissectionComputed tomographyForensic pathologyPolycystic kidney disease

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