Primary Cardiac Tumors in Infancy: A Case Report and Literature Review

Carolina Dominguez1, Ashley Perkins1, Alexandra Duque2

  • 1University of South Florida - Pathology and Cell Biology.

Insights

Sudden infant death from primary cardiac tumors is rare. A case report details an 8-month-old infant whose death was caused by a left ventricular fibroma, leading to cardiogenic shock.

Area of Science:

  • Pediatric Pathology
  • Cardiovascular Medicine
  • Forensic Science

Background:

  • Sudden death in infants is uncommon, with primary cardiac tumors being an exceedingly rare cause.
  • This case involves an 8-month-old male infant presenting with sudden cyanosis and loss of consciousness after feeding.

Purpose of the Study:

  • To report a rare case of sudden infant death attributed to a primary cardiac tumor.
  • To elucidate the cause, manner, and mechanism of death through forensic autopsy and histological examination.

Main Methods:

  • Forensic autopsy of an 8-month-old infant with a history of sudden collapse.
  • Histological examination of a cardiac mass identified during autopsy.
  • Clinical correlation of autopsy findings with reported events.

Main Results:

  • Autopsy revealed a eutrophic infant with cyanosis and no signs of external trauma.
  • A single, white, whorled cardiac tumor was found in the anterior wall of the left ventricle.
  • Histological diagnosis confirmed the tumor as a fibroma.

Conclusions:

  • The infant's death was attributed to cardiogenic shock resulting from a primary cardiac fibroma.
  • This case highlights the potential for cardiac fibromas to cause sudden, fatal events in infants.
  • Emphasizes the importance of considering cardiac pathology in unexplained sudden infant deaths.

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