Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Cell Death01:30

Overview of Cell Death

9.6K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
9.6K
Autophagic Cell Death01:18

Autophagic Cell Death

4.4K
Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
4.4K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

498
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
498
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

1.1K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.1K
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

556
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
556
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

425
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
425

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic tensile loading improves neotendon formation at moderate daily loading cycles, but impairs neotendon formation at high daily loading cycles.

Journal of biomechanics·2026
Same author

Tendon Omics: A Survey-Based Perspective on Obstacles and Opportunities.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same author

Strain-conditioned spatial gene expression in female mouse bone under physiological and non-physiological strain distribution.

JBMR plus·2026
Same author

Difference in Upper Limb Length Measurements Between Different Methods at External Postmortem Examination: Implication for Gunshot-Related Deaths.

The American journal of forensic medicine and pathology·2025
Same author

The role of legal medicine in the reconstruction of fatalities due to tractor rollovers: from evidence to proof.

Legal medicine (Tokyo, Japan)·2025
Same author

Impact of Polymer Degradation on Cellular Behavior in Tissue Engineering.

Bioprinting (Amsterdam, Netherlands)·2025

Related Experiment Video

Updated: Jan 23, 2026

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
10:08

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants

Published on: December 21, 2021

2.6K

Maternal Death and Its Investigation.

Jack Garland, Dianne Little

    Academic Forensic Pathology
    |June 27, 2019
    PubMed
    Summary

    Maternal deaths, a critical global health issue, disproportionately affect developing nations. This review details pregnancy-related deaths and autopsy guidelines to aid in reducing mortality rates.

    Area of Science:

    • Obstetrics and Gynecology
    • Pathology
    • Global Health

    Background:

    • Maternal deaths remain a significant cause of mortality in young females globally, with stark disparities between developing (240/100,000 live births) and developed regions (16/100,000 live births).
    • Maternal deaths are categorized into direct (obstetric complications), indirect (aggravated pre-existing conditions), and incidental (unrelated causes).
    • The impact of maternal mortality extends beyond the individual, affecting families and communities, highlighting the need for comprehensive data collection and analysis.

    Purpose of the Study:

    • To review the clinical and pathological characteristics of common pregnancy-related disorders.
    • To provide guidelines for conducting autopsies in cases of maternal death.
    • To emphasize the pathologist's role in understanding and mitigating maternal mortality.
    Keywords:
    AutopsyForensic pathologyMaternal death

    More Related Videos

    Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
    06:55

    Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

    Published on: December 5, 2015

    14.1K
    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish
    09:17

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

    Published on: July 22, 2025

    810

    Related Experiment Videos

    Last Updated: Jan 23, 2026

    Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
    10:08

    Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants

    Published on: December 21, 2021

    2.6K
    Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
    06:55

    Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

    Published on: December 5, 2015

    14.1K
    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish
    09:17

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

    Published on: July 22, 2025

    810

    Main Methods:

    • Review of clinical presentations of pregnancy-related disorders.
    • Pathological examination of maternal death cases.
    • Development of standardized autopsy protocols for maternal deaths.

    Main Results:

    • Detailed description of the clinical and pathological findings in various direct, indirect, and incidental maternal deaths.
    • Identification of key autopsy findings that can elucidate the cause of death.
    • Establishment of a framework for systematic pathological investigation of maternal mortality.

    Conclusions:

    • Understanding the clinical and pathological aspects of maternal deaths is crucial for accurate diagnosis and prevention.
    • Standardized autopsy procedures are essential for reliable data collection and contributing to public health initiatives.
    • Pathological review plays a vital role in the global effort to reduce maternal mortality rates.