Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

2.8K
The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the...
2.8K
Initiation of Translation02:33

Initiation of Translation

38.4K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
38.4K
Initiation of Translation02:33

Initiation of Translation

8.0K
8.0K
Transcription Initiation01:47

Transcription Initiation

20.5K
Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
20.5K
Components of Stress01:23

Components of Stress

509
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
509
Components of Language01:24

Components of Language

776
Language, whether spoken, signed, or written, consists of specific components: lexicon and grammar. The lexicon is the vocabulary of a language, comprising its words. Grammar is the set of rules used to convey meaning through the lexicon. For example, English grammar adds “-ed” to most verbs to indicate past tense. Words are formed by combining phonemes, which are the basic sound units of a language. Different languages have different sets of phonemes (e.g., “ah” vs.
776

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Olefination of Alcohols and Alkyl Halides via Oxidative Alkyl Electrophile-Olefin Metathesis.

Organic letters·2026
Same author

Initiating Photocontrolled Atom Transfer Radical Polymerization from a Redox-Activated Functional Group.

Journal of the American Chemical Society·2026
Same author

Grafting polymer brushes from nylon surfaces <i>via</i> hydrogen atom transfer.

Chemical science·2026
Same author

Surface-Initiated Hydrogen Atom Transfer Reversible Addition-Fragmentation Chain Transfer Polymerization from Isotactic Polypropylene.

Macromolecules·2026
Same author

Leveraging Mechanistic Insights into Stereoretentive ROMP for Precision Synthesis of Poly(<i>p</i>-phenylene vinylene)s.

Journal of the American Chemical Society·2026
Same author

Universal Approach for the Depolymerization of Polyamides via Photothermal Conversion.

Journal of the American Chemical Society·2026
Same journal

Proton-Gated Torsional Spring for Molecular Energy Storage.

Journal of the American Chemical Society·2026
Same journal

Topologically Programmed Dual-Channel Covalent Organic Frameworks Decouple Gas and Ion Fluxes for Acidic CO<sub>2</sub> Electroreduction.

Journal of the American Chemical Society·2026
Same journal

Plasmonic Re-Excitation Enables Superoxide-Mediated Ethane Conversion to Acetic Acid under Visible Light.

Journal of the American Chemical Society·2026
Same journal

Photocatalytic Controlled Halodefluorination of Perfluoroalkyl Compounds Using <i>N</i>-Arylphenothiazines.

Journal of the American Chemical Society·2026
Same journal

Photoinduced Disproportionation Enables Oxidative Addition of Aryl Iodides at a Gallium(I) Center.

Journal of the American Chemical Society·2026
Same journal

Biocatalytic C3 β-<i>O</i>-Glycosylation of Triterpenes and Sterols to Synthesize Natural and Unnatural Saponins.

Journal of the American Chemical Society·2026
See all related articles

Related Experiment Video

Updated: Jan 23, 2026

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions
15:00

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions

Published on: June 14, 2016

11.2K

Controlled Cationic Polymerization: Single-Component Initiation under Ambient Conditions.

Veronika Kottisch1, Jacob O'Leary1, Quentin Michaudel1

  • 1Cornell University , Ithaca , New York 14853 , United States.

Journal of the American Chemical Society
|June 27, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces pentacarbomethoxycyclopentadiene (PCCP) as a novel initiator for cationic polymerization. It enables controlled vinyl ether polymerization under ambient conditions with high chain-end fidelity, simplifying polymer synthesis.

More Related Videos

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
10:54

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization

Published on: June 19, 2015

10.2K
Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

Published on: May 19, 2014

18.8K

Related Experiment Videos

Last Updated: Jan 23, 2026

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions
15:00

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions

Published on: June 14, 2016

11.2K
Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
10:54

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization

Published on: June 19, 2015

10.2K
Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

Published on: May 19, 2014

18.8K

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Macromolecular Science

Background:

  • Cationic polymerization offers precise macromolecule synthesis but demands stringent conditions like low temperatures and anhydrous environments.
  • Sensitivity to impurities often necessitates extensive reagent purification, complicating the process.

Purpose of the Study:

  • To develop a simplified and robust method for cationic polymerization.
  • To achieve controlled polymerization of vinyl ethers under ambient conditions.
  • To maintain high chain-end fidelity without rigorous monomer purification.

Main Methods:

  • Utilized pentacarbomethoxycyclopentadiene (PCCP) as a single-component initiating organic acid.
  • Investigated the polymerization of a diverse library of vinyl ethers.
  • Employed functional nucleophiles for chain-end termination.

Main Results:

  • Achieved controlled polymerization of vinyl ethers using PCCP under ambient conditions.
  • Demonstrated excellent chain-end fidelity, even with unpurified monomers.
  • Successfully functionalized polymer chain-ends in high yields via nucleophilic termination.

Conclusions:

  • PCCP acts as an effective initiator for ambient cationic polymerization of vinyl ethers.
  • A proposed tight ion complex mechanism explains the observed living characteristics and high fidelity.
  • This method offers a practical approach to controlled polymer synthesis and functionalization.