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Updated: Jan 23, 2026

In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing
Published on: February 6, 2018
Warming nerves for excitability testing
Maria O Kovalchuk1, Hessel Franssen1, Féline E V Scheijmans1
1Department of Neurology, University Medical Center Utrecht, Brain Center, Utrecht University, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Introduction:
The aim of this study was to find the best method of warming the median nerve before excitability testing to a standard temperature.
Methods:
In 5 healthy subjects, the forearm and hand were warmed for 1 h to 37°C by infrared lamp, water blanket, or water bath. Recordings were performed before and during warming every 10 min. Excitability indices were fitted by exponential relations, thereby calculating the time needed to reach 95% of their asymptotic end value.
Results:
Distal motor latency, refractory period, and superexcitability at 10 ms changed exponentially with time. Warming by water bath took the shortest time (24 min); this was followed by warming by infrared lamp (34 min) and water blanket (35 min).
Conclusions:
Warming by water bath is the quickest way. The other methods took only moderately more time. Future studies need to specify both warming method and warming time before excitability testing. Muscle Nerve, 2019.
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