Identification of a Multiplex Biomarker Panel for Hypertrophic Cardiomyopathy Using Quantitative Proteomics and

Gabriella Captur1, Wendy E Heywood2, Caroline Coats3

  • 1UCL MRC Unit for Lifelong Health and Ageing, 1-19 Torrington Place, Fitzrovia, London WC1E 7HB, UK; Barts Heart Center, The Cardiovascular Magnetic Resonance Imaging Unit and The Inherited Cardiovascular Diseases Unit, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK.

Summary

New plasma biomarkers for hypertrophic cardiomyopathy (HCM) can improve disease monitoring and sudden cardiac death (SCD) risk assessment. Six peptides identified show promise in detecting HCM and stratifying risk, aiding early intervention for this inherited cardiac condition.

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