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A new proof for the relationship between erectile dysfunction and atherosclerosis: fragmented QRS?
Mehmet Karabakan1, Aliseydi Bozkurt2, Barıs Saylam3
1Department of Urology, Mersin Toros State Hospital, Mersin, Turkey. mkarabakan@yandex.com.
International Journal of Impotence Research
|June 28, 2019
Summary
Fragmented QRS (fQRS) on ECG may indicate myocardial ischemia in patients with coronary artery disease. This study found higher fQRS rates in men with erectile dysfunction (ED), suggesting fQRS as an early sign of cardiovascular disease in ED patients.
Area of Science:
- Cardiology
- Men's Health
- Diagnostic Markers
Background:
- Fragmented QRS (fQRS) on electrocardiography (ECG) is a marker of myocardial ischemia in coronary artery disease (CAD).
- Erectile dysfunction (ED) is an early sign and independent predictor of CAD.
- The relationship between fQRS and ED has not been previously investigated.
Purpose of the Study:
- To investigate the association between fQRS and ED.
- To determine if fQRS can serve as an early indicator of CAD in patients with ED.
Main Methods:
- A study involving 190 male patients with varying degrees of ED and 51 healthy controls.
- ECG analysis to detect the presence of fQRS.
- Comparison of fQRS rates across ED severity groups and the control group.
Main Results:
- Significantly higher fQRS prevalence in severe (27.5%), moderate (23.5%), and mild-to-moderate (22.5%) ED groups compared to mild ED (13.7%) and control (12.7%) groups (p < 0.001).
- fQRS was found to be significantly associated with the presence and severity of ED.
Conclusions:
- fQRS detected via ECG may be an early indicator of underlying CAD in men presenting with ED.
- Incorporating fQRS assessment into the evaluation of ED patients could prompt further cardiac diagnostics for cardiovascular disease.
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