Determination of glycemic index of enteral formulas used in clinical practice

Glycemic Index (GI) is a measure of carbohydrate quality and is recognised as a valid and reproducible method of classifying carbohydrate foods according to its effects on postprandial glycaemia. In this randomised crossover trial (RBR-7rjx3k) we determined the GI of nine enteral formulas, following the Food and Agriculture Organisation/World Health Organisation method. Forty healthy participants were included in the study (85% female mean age 27.1 ± 6.7 years). GI of the enteral formulas ranged from 40.5 to 85.2; four formulas had high GI (Nutrienteral 1.5^®, Novasource GI Control^®, Diamax^®, Isosource Soya^®), two intermediate GI (Fresubin 1.2 HP Fibre^®, Nutrison Energy Multifiber 1.5^®) and three low GI (Trophic 1.5^®, Glucerna^®, Novasource GC HP^®). The GI coefficient of variation ranged from 22.9% to 83.6%. The effect of the enteral formulas with low GI in glycemic control of patients with enteral nutrition prescription needs to be test in future studies.