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Updated: Jan 22, 2026
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A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities
Published on: October 3, 2008
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Precise cell behaviors manipulation through light-responsive nano-regulators: recent advance and perspective.
Do Cong Thang1, Zhimin Wang1, Xiaoling Lu2
1Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Theranostics
|June 28, 2019
Summary
Light-responsive nanomedicine enables precise control over cellular functions for precision medicine. These advancements offer new therapeutic strategies for diseases by manipulating biological events with light.
Area of Science:
- Biomedical Engineering
- Nanomedicine
- Cellular Biology
Background:
- Nanotechnology offers precise spatiotemporal control over biological events, crucial for advancing precision medicine.
- Stimuli-responsive nanoplatforms are key for targeted cellular regulation and theranostics, with potential clinical applications.
- Light-responsive nanoregulators are gaining attention for their ability to precisely manipulate cell functions.
Purpose of the Study:
- To review the current developments in light-activatable nanoplatforms for modulating cellular events.
- To highlight the potential of nanomedicine in precision healthcare.
- To explore applications in neuromodulation, stem cell monitoring, immunomanipulation, and cancer therapy.
Main Methods:
- Review of literature on light-responsive nanoplatforms.
- Analysis of UV-Vis and near-infrared (NIR) light-triggered mechanisms.
- Discussion of applications in various biological and medical contexts.
Main Results:
- Light-activatable nanoplatforms demonstrate precise control over cellular functions.
- UV-Vis light triggers photocleavage and photoisomerization for specific cellular tasks.
- NIR light enables deep-tissue applications for disease treatment and cellular signaling.
Conclusions:
- Light-controlled nanomedicine presents a promising future for revolutionary medical treatments.
- Precise manipulation of cellular events via nanoregulators can lead to significant clinical advancements.
- The integration of nanotechnology and light offers powerful tools for precision medicine.
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