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Patient-centered drug development and the Learning Health System
Laura S Crawford1, Gerald J Matczak2, Erin M Moore3
1Global Patient Outcomes and Real World Evidence Eli Lilly and Company Indianapolis Indiana.
Learning Health Systems
|June 28, 2019
Summary
Patient-centered drug development (PCDD) integrates patient input throughout the drug creation process. A Learning Health System can overcome PCDD challenges by improving data flow and stakeholder connections.
Area of Science:
- Pharmacology and Pharmaceutical Sciences
- Health Services Research
- Patient Engagement
Background:
- Traditional drug development often overlooks patient needs and values.
- Systematic patient participation is crucial for creating effective medicines.
- Understanding patient perspectives enhances drug development efficiency.
Purpose of the Study:
- To define Patient-Centered Drug Development (PCDD).
- To illustrate PCDD implementation across drug development phases.
- To identify challenges and propose solutions for systematic PCDD.
Main Methods:
- Literature review and conceptual framework development.
- Analysis of existing PCDD initiatives.
- Exploration of the role of Learning Health Systems.
Main Results:
- PCDD involves patients in all stages of drug development.
- Examples of PCDD application are provided.
- Barriers to systematic PCDD include data integration and stakeholder alignment.
Conclusions:
- Patient-centered drug development leads to more meaningful outcomes.
- Learning Health Systems offer a framework to address PCDD challenges.
- Enhanced data flow and governance are key to successful PCDD.
Keywords:
Learning Health NetworkLearning Health Systemclinical researchdrug approvaldrug developmentmedicines developmentpatient centeredpatient centricpatient engagementpatient focusedpatient participationpatient‐centered drug developmentMore Related Videos
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