Related Experiment Video
Updated: Jan 22, 2026

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
Published on: August 31, 2015
Ranking Oxidant Sensitiveness: A Guide for Synthetic Utility
Madeleine A Dallaston1, Christian J Bettencourt1, Sharon Chow1
1School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, 4072, Australia.
Abstract:
Common oxidants used in chemical synthesis, including newly developed perruthenates, were evaluated in the context of understanding (and better appreciating) the sensitiveness and associated potential hazards of these reagents. Analysis using sealed cell differential scanning calorimetry (scDSC) facilitated Yoshida correlations, which were compared to impact sensitiveness and electrostatic discharge experiments (ESD), that enabled sensitiveness ranking. Methyltriphenylphoshonium perruthenate (MTP3, 8), isoamyltriphenylphosphonium perruthenate (ATP3, 7) and tetraphenylphosphonium perruthenate (TP3, 9) were found to be the most sensitive followed by 2-iodoxybenzoic acid (IBX, 2) and benzoyl peroxide (BPO, 10), whereas the most benign were observed to be Oxone (12), manganese dioxide (MnO2 , 13), and N-bromosuccinimide (NBS, 17).
More Related Videos
Related Concept Videos
Ranks
Spearman's Rank Correlation Test
Spearman's test calculates correlation by...
Wilcoxon Rank-Sum Test
Friedman Two-way Analysis of Variance by Ranks
The Mantel-Cox Log-Rank Test
Oxidation Numbers

