Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.2K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.2K
Fixed Action Patterns01:06

Fixed Action Patterns

17.5K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.5K
Patterns of Fever01:26

Patterns of Fever

3.8K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.8K
Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

1.2K
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
1.2K
¹H NMR Signal Multiplicity: Splitting Patterns01:13

¹H NMR Signal Multiplicity: Splitting Patterns

6.5K
When protons A and X are coupled, their nuclear spin energy levels are slightly modified. This is because the energy required to excite proton A to a spin state parallel to proton X is slightly different from the energy required for it to become anti-parallel to spin X. Consequently, there are two possible excitation frequencies for A (A1 and A2), depending on the spin state of X, and vice versa. The mutual nature of coupling implies that the difference between frequencies A1 and A2, indicated...
6.5K
Assessment of the Gastrointestinal System II: Health Perception Pattern01:29

Assessment of the Gastrointestinal System II: Health Perception Pattern

463
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
463

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sarcoidosis and Systemic Comorbidities: Sex-Related Differences in a Multicenter Italian Cohort.

Respiration; international review of thoracic diseases·2026
Same author

Inter-centre heterogeneity, temporal evolution, and factors associated with treatment selection and outcomes in chronic inflammatory demyelinating polyradiculoneuropathy: a multicentre, combined prospective and retrospective observational study.

EClinicalMedicine·2026
Same author

Pragmatic cluster-randomised trial of a multidomain intervention to prevent hospital-acquired disability: the OPTIMAge-IT study protocol.

BMC geriatrics·2026
Same author

Bone involvement in sarcoidosis: Insights from a multicentre Italian cohort.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG·2026
Same author

ChatGPT in the diagnosis and management of complex polyneuropathies: comparative analysis with neurologists using real-world cases.

NPJ digital medicine·2026
Same author

Correction: Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis.

Molecular neurodegeneration·2026

Related Experiment Video

Updated: Jan 22, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

2.1K

Prognostic patterns and predictors in epilepsy: a multicentre study (PRO-LONG).

Ettore Beghi1, Simone Beretta2, Davide Carone2

  • 1Laboratory of Neurological Disorders, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy ettore.beghi@marionegri.it.

Journal of Neurology, Neurosurgery, and Psychiatry
|June 29, 2019
PubMed
Summary

Few seizures, generalized epilepsy, and no psychiatric issues predict long-term seizure freedom in epilepsy patients. However, remission does not guarantee an end to future seizures.

Keywords:
epilepsylong-term prognosisprognostic patternsprognostic predictors

More Related Videos

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

545
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.9K

Related Experiment Videos

Last Updated: Jan 22, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

2.1K
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

545
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

12.9K

Area of Science:

  • Neurology
  • Epileptology

Background:

  • Epilepsy prognosis and long-term outcomes are crucial for patient management.
  • Understanding prognostic patterns can guide treatment strategies and patient counseling.

Purpose of the Study:

  • To describe the long-term prognosis and identify prognostic patterns in a large cohort of newly diagnosed epilepsy patients.
  • To identify factors influencing epilepsy remission and relapse.

Main Methods:

  • A retrospective cohort study involving 1006 patients from 13 Italian epilepsy centers with at least 10 years of follow-up.
  • Data collection included demographics, seizure characteristics, comorbidities, treatments (antiepileptic drugs - AEDs), and seizure remission at 1, 2, 5, and 10 years.
  • Prognostic patterns (early remission, late remission, relapsing-remitting, worsening, no remission) were identified, and prognostic factors were analyzed using multinomial logistic regression.

Main Results:

  • 91.7% achieved 1-year remission, with 44.4% achieving 10-year remission.
  • Five-year remission was linked to fewer seizures at diagnosis, generalized epilepsy, no psychiatric comorbidity, and 1-2 AEDs.
  • The most common pattern was relapsing-remitting (52.2%), while 8.3% had no remission.

Conclusions:

  • Fewer seizures at diagnosis, generalized epilepsy, and absence of psychiatric comorbidity are predictors of seizure freedom.
  • Achieving remission at any point does not preclude future relapses, highlighting the chronic nature of epilepsy for some individuals.