A randomised bite force study assessing two currently marketed denture adhesive products compared with no-adhesive...

Area of Science:

• Oral care technology
• Dental materials science
• Prosthodontics

Background:

• Limited denture adhesive technologies exist, primarily using polymethyl vinyl ether/maleic anhydride (PVM/MA) polymers.
• Carbomer-based denture adhesives are less researched, with few comparative clinical studies against PVM/MA formulations.

Purpose of the Study:

• To compare the clinical performance of a carbomer-based denture adhesive against a PVM/MA-based adhesive and a no-adhesive control.
• To evaluate denture adhesive efficacy using incisal bite force measurements over a 12-hour period.

Main Methods:

• A single-center, randomized, examiner-blind, crossover study involving participants with complete maxillary dentures.
• Participants underwent incisal bite force testing (area over baseline over 12 hours; AOB0-12) at baseline and multiple time points up to 12 hours post-application.
• Denture dislodgement force was measured using a transducer after application of carbomer adhesive, PVM/MA adhesive, or no adhesive.

Main Results:

• Both carbomer-based (Test) and PVM/MA-based (Reference) adhesives significantly improved denture retention compared to no adhesive (p < 0.0001).
• The difference in AOB0-12 between the Test and Reference adhesives was not statistically significant (p = 0.1555), indicating comparable performance.
• Both adhesive formulations were generally well-tolerated by participants.

Conclusions:

• Carbomer-based and PVM/MA-based denture adhesives provide statistically significant improvements in denture retention over 12 hours.
• There is no statistically significant difference in denture retention efficacy between carbomer and PVM/MA denture adhesives.
• Both tested denture adhesive technologies are effective and comparable in enhancing denture stability.