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Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report
Cristina Sarda1, Giulia Magrini2, Sfefano Pelenghi3
1Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.
Cureus
|June 29, 2019
Summary
Group A Streptococcus pyogenes infective endocarditis (IE) is rare. This case highlights successful antibiotic treatment of Streptococcus pyogenes native mitral valve endocarditis, avoiding surgery.
Area of Science:
- Cardiology
- Infectious Diseases
- Microbiology
Background:
- Infective endocarditis (IE) is a serious infection of the heart's inner lining.
- Group A beta-hemolytic streptococcus (Streptococcus pyogenes) is an uncommon cause of IE.
Observation:
- A young patient presented with native mitral valve endocarditis caused by Streptococcus pyogenes.
- The patient had a vegetation on the mitral valve but remained hemodynamically stable.
Findings:
- Initial treatments included cefixime, azithromycin, vancomycin, and amoxicillin-clavulanate.
- Subsequent targeted therapy with gentamicin and ampicillin led to vegetation resolution.
- Weekly echocardiography monitored treatment effectiveness.
Implications:
- This case demonstrates the feasibility of non-surgical management for Streptococcus pyogenes IE.
- Successful antibiotic regimens can be crucial for patients with IE.
- Further research into Streptococcus pyogenes IE treatment is warranted.
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