Related Experiment Video

Updated: Jan 22, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
09:13

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

Published on: June 14, 2017

13.4K

Mitral Valve Infective Endocarditis due to Streptococcus pyogenes: A Case Report

Cristina Sarda1, Giulia Magrini2, Sfefano Pelenghi3

  • 1Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, ITA.

Cureus
|June 29, 2019
PubMed

Insights

Group A Streptococcus pyogenes infective endocarditis (IE) is rare. This case highlights successful antibiotic treatment of Streptococcus pyogenes native mitral valve endocarditis, avoiding surgery.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Microbiology

Background:

  • Infective endocarditis (IE) is a serious infection of the heart's inner lining.
  • Group A beta-hemolytic streptococcus (Streptococcus pyogenes) is an uncommon cause of IE.

Observation:

  • A young patient presented with native mitral valve endocarditis caused by Streptococcus pyogenes.
  • The patient had a vegetation on the mitral valve but remained hemodynamically stable.

Findings:

  • Initial treatments included cefixime, azithromycin, vancomycin, and amoxicillin-clavulanate.
  • Subsequent targeted therapy with gentamicin and ampicillin led to vegetation resolution.
  • Weekly echocardiography monitored treatment effectiveness.

Implications:

  • This case demonstrates the feasibility of non-surgical management for Streptococcus pyogenes IE.
  • Successful antibiotic regimens can be crucial for patients with IE.
  • Further research into Streptococcus pyogenes IE treatment is warranted.
Keywords:
infective endocarditisstreptococcus pyogenes

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.3K
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

4.3K

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
446
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
416
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
472
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
314
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
414
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
219