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Difficulties arising in reimbursement recommendations on new medicines due to inadequate reporting of population
Eileen M Holmes1,2, Joy Leahy3, Cathal D Walsh4
1Dundee Epidemiology and Statistics Unit, University of Dundee, Dundee, UK.
Abstract:
Indirect treatment comparisons are useful to estimate relative treatment effects when head-to-head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost-effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population-adjustment indirect comparison methods is causing uncertainty in our recommendations to decision-making committees when assessing reimbursement of medicines.
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