SAPHO Syndrome in an Adult Male with Ulcerative Colitis

Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) syndrome refers to a rare entity expressed by a combination of dermatological and osteoarticular manifestations. We report a case of this unique syndrome initially diagnosed as "Sweet's syndrome" due to more or less similar features. The patient is also a diagnosed case of ulcerative colitis, a rare association with SAPHO syndrome. The clinical picture, laboratory findings and most of all radiological features, ultimately directed us towards the final diagnosis. The purpose of this case report is to raise awareness regarding this unusual syndrome, its clinical manifestations, laboratory and radiological findings, so that proper management can be carried out in time.