Related Experiment Video
Updated: Jan 22, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Is personal oral hygiene advice effective in preventing coronal dental caries?
1School of Dentistry, University of Dundee, Dundee, UK. N.P.Innes@dundee.ac.uk.
Abstract:
Data sources PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials databases.Study selection PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials databases were searched for studies published in English between January 1950 and February 2017.Data extraction and synthesis Data were extracted independently by two reviewers and risk of bias assessed using a modified Jadad scale. Heterogeneity was evaluated using the chi-squared statistic and meta-analysis performed.Results Three randomised trials were included, involving 681 participants; all children 10-13 years old. Two trials were conducted in the USA and one in the UK. Two studies tested school-based, daily supervised oral hygiene (including plaque staining and removal and supervised flossing) against control groups; one study tested the same intervention every two weeks against controls. Two studies measured decayed, missing or filled surfaces (DMFS) scores at three years and one trial at 29 months. Personal oral hygiene interventions failed to influence the incidence of dental caries, (DMFS = -0.11; 95% CI -0.91, 0.69: P value <0.79). Four non-randomised trials were retained to conduct sensitivity analyses.Conclusions Personal oral hygiene interventions delivered to school children failed to show a reduction in coronal dental carious lesion incidence over three years when compared to control groups.
Related Concept Videos
Psychosexual Stages of Personality: Oral
Weaning, typically occurring...
Hand hygiene
Hand washing...
Cancer Prevention
Some...
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Personal Identity
Prevention of Further Absorption of Poison

