French-style genetics v. 2.0: The "e-CohortE" project

Area of Science:

• Genomics
• Bioinformatics
• Public Health

Background:

• Genetics cohorts have evolved beyond disease causation to become data-generating platforms.
• Private companies like 23andMe exemplify the commercial and scientific exploitation of genetic data through two-sided markets.
• Current French law restricts foreign private genetic companies and similar domestic entities.

Purpose of the Study:

• To propose a novel theoretical model for a French genetics cohort, termed 'e-CohortE'.
• To adapt the successful 'two-sided market' concept for genomic studies within the French healthcare system.
• To enable genomic research and multi-subject questionnaires without necessitating legal changes.

Main Methods:

• Conceptualizing a new cohort model inspired by commercial two-sided markets.
• Integrating features specific to the French healthcare management system.
• Designing a framework for genomic studies combined with multi-subject questionnaires.

Main Results:

• Identification of a legal and operational gap for advanced genetics cohorts in France.
• Theoretical proposal of 'e-CohortE' as a viable solution.
• Demonstration that such a model can be developed within existing French legal parameters.

Conclusions:

• France can develop its own advanced genetics cohort model, 'e-CohortE'.
• 'e-CohortE' offers a way to leverage genomic data for research and healthcare innovation.
• This theoretical model aligns with French healthcare principles while capitalizing on data-driven insights.