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Ap4A Regulates Directional Mobility and Antigen Presentation in Dendritic Cells.

Shin La Shu1, Lakshmi Bhargavi Paruchuru2, Neil Quanwei Tay1

  • 1Immunology Programme, Department of Microbiology, Centre for Life Sciences, National University of Singapore, #03-09, 28 Medical Drive, Singapore 117456, Singapore; NUS-HUJ-CREATE, 1 Create Way, Innovation Wing #03-09, Singapore 138602, Singapore.

Iscience
|June 30, 2019
PubMed
Summary

Elevated diadenosine tetraphosphate (Ap4A) levels in dendritic cells (DCs) enhance their immune functions. This study used Nudt2-deficient mice to show Ap4A

Keywords:
Immune ResponseImmunologyModel OrganismMolecular Mechanism of Behavior

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