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Multicenter Investigation of Fungal Infections of Inflatable Penile Prostheses
Martin S Gross1, Lael Reinstatler1, Gerard D Henry2
1Section of Urology, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
The Journal of Sexual Medicine
|July 1, 2019
Summary
Fungal infections of inflatable penile prostheses (IPPs) are uncommon but primarily affect diabetic or overweight individuals. Antifungal prophylaxis may be beneficial for these high-risk patients undergoing IPP surgery.
Area of Science:
- Urology
- Infectious Diseases
- Prosthetics
Background:
- Fungal infections of inflatable penile prostheses (IPPs) are poorly documented in medical literature.
- Understanding patient and surgical factors associated with fungal IPP infections is crucial for prevention and management.
Purpose of the Study:
- To investigate common patient and surgical characteristics linked to fungal infections in IPPs.
- To analyze a multi-institution database of IPP infections to identify risk factors for fungal etiologies.
Main Methods:
- Retrospective analysis of 217 patients from 26 institutions undergoing IPP salvage or explant between 2001 and 2018.
- Data compilation involved extensive review of patient records.
- Focus on identifying cases of fungal IPP infections.
Main Results:
- Fungal infections were identified in 26 patients (12%) of the total cohort.
- The majority of fungal infections (83%) occurred in patients who were either diabetic or overweight.
- Diabetic patients (69%) had a mean HbA1c of 8.4, and 85% of patients were overweight or obese (mean BMI 30.1 kg/m²).
Conclusions:
- Fungal infections constitute a significant portion (12%) of IPP infections in this series.
- Diabetic and overweight/obese patients represent the primary demographic for fungal IPP infections.
- Consideration of antifungal prophylaxis is warranted for diabetic and overweight patients undergoing IPP implantation.
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