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Updated: Jan 22, 2026

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Marginal bone loss one year after implantation: a systematic review of different loading protocols
M Sommer1, J Zimmermann1, L Grize2
1Hightech Research Centre, Department of Biomedical Engineering, University of Basel, Basel, Switzerland.
Summary
Immediate implant loading shows minimal marginal bone loss (MBL), making it a viable alternative to conventional loading. This analysis of dental implant protocols confirms immediate loading offers comparable outcomes with reduced bone loss.
Area of Science:
- Dental Implantology
- Biomaterials Science
- Oral Surgery
Background:
- Marginal bone loss (MBL) is a critical factor in long-term dental implant success.
- Various implant loading protocols exist, each with potential implications for MBL.
Purpose of the Study:
- To analyze the influence of different dental implant loading protocols on marginal bone loss (MBL) at one year.
- To compare MBL across immediate, immediate non-occlusal, early, and conventional loading protocols.
Main Methods:
- Systematic review and meta-analysis of 889 identified studies.
- Inclusion of 22 studies assessing MBL at one year post-implantation.
- Statistical analysis of MBL data for different loading protocols.
Main Results:
- Immediate loading exhibited the lowest MBL (0.457mm), while conventional loading showed the highest (0.852mm).
- Conventional loading demonstrated significantly higher MBL compared to immediate, immediate non-occlusal, and early loading.
- Immediate loading showed the lowest decrease in 1-year implant survival per millimeter increase in MBL.
Conclusions:
- Immediate implant loading is a reasonable and effective alternative to conventional loading.
- The immediate loading protocol appears to minimize marginal bone loss effectively.
- Evidence supports immediate loading for predictable long-term dental implant outcomes.
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