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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
An update on the current management of adult obstructive sleep apnoea
Lernik Sarkissian1, Leon Kitipornchai2, Peter Cistulli3
1BAppScExSS, MPhty, MBBS, Otolaryngology, Head @ Neck registrar, Wollongong Hospital; Illawarra ENT Head and Neck Clinic Wollongong, NSW. ls095@uowmail.edu.au.
Background:
Obstructive sleep apnoea (OSA) is common in adults. Various contributing factors to this condition have resulted in the development of a number of potential treatment modalities, some of which are in evolution. A multidisciplinary team involving the general practitioner is an important aspect in providing personalised care.
Objective:
The aim of this review is to provide a clinical update on the recent developments and future directions in adult OSA management.
Discussion:
In-lab polysomnography remains important in the diagnosis of OSA, although home sleep studies have good specificity and sensitivity in particular subgroups of patients. First-line therapy in adult OSA is continuous positive airway pressure, with mandibular advancement splints and surgical intervention considered second-line. Adjunctive therapies include weight loss, avoidance of supine sleep, management of nasal obstruction, alcohol intake limitation and exercise. Advancements in medications targeting multiple neurophysiological pathways, and surgical insertion of hypoglossal nerve stimulator devices represent possible future treatment pathways in Australia.
Insights
Obstructive sleep apnoea (OSA) management is evolving, with continuous positive airway pressure as a first-line therapy. Future directions include new medications and hypoglossal nerve stimulation for adult OSA.
Area of Science:
- Sleep Medicine
- Respiratory Medicine
- Otolaryngology
Background:
- Obstructive sleep apnoea (OSA) is a prevalent condition in adults.
- Multiple factors contribute to OSA, necessitating diverse treatment approaches.
- Multidisciplinary care, including general practitioners, is crucial for personalized OSA management.
Purpose of the Study:
- To provide a clinical update on recent advancements in adult OSA management.
- To explore future directions and emerging therapies for adult OSA.
Main Methods:
- Review of current diagnostic methods for OSA, including polysomnography and home sleep studies.
- Analysis of established and emerging treatment modalities for adult OSA.
- Examination of adjunctive therapies and lifestyle modifications for OSA management.
Main Results:
- In-lab polysomnography remains a key diagnostic tool, with home sleep studies offering good specificity/sensitivity in select populations.
- Continuous positive airway pressure (CPAP) is the primary treatment for adult OSA.
- Mandibular advancement splints and surgery are second-line options, alongside lifestyle interventions like weight loss and exercise.
Conclusions:
- Current management strategies for adult OSA involve a combination of established therapies and lifestyle adjustments.
- Emerging treatments, including novel medications and hypoglossal nerve stimulation, show promise for future OSA management.
- Personalized care and a multidisciplinary approach are essential for optimizing outcomes in adult OSA patients.
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