Related Experiment Video

Updated: Jan 22, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

23.6K

Methicillin-Resistant Staphylococcus aureus in Diabetic Foot Infection in India: A Growing Menace

Vijay Viswanathan1, Sharad Pendsey2, Chandni Radhakrishnan3

  • 1M V Centre for Diabetes, Chennai, Tamil Nadu, India.

The International Journal of Lower Extremity Wounds
|July 2, 2019
PubMed

Insights

Diabetic foot infections (DFI) are serious, often polymicrobial, and increasingly resistant to treatment, particularly methicillin-resistant Staphylococcus aureus (MRSA). New therapeutic strategies are urgently needed to combat MRSA in DFI patients.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Endocrinology

Background:

  • Diabetic foot infections (DFI) are a severe complication of diabetes mellitus, frequently caused by polymicrobial pathogens.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen in DFI, linked to higher treatment failure and hospitalization costs.
  • Limited treatment options and increasing antimicrobial resistance pose major challenges in managing DFI.

Purpose of the Study:

  • To review current therapeutic trends for diabetic foot infections.
  • To highlight challenges in treating DFI, especially those caused by MRSA.
  • To provide an overview of novel drugs under development for MRSA infections.

Main Methods:

  • Literature review of ongoing therapeutic trends in DFI management.
  • Analysis of challenges associated with DFI treatment.
  • Overview of emerging anti-MRSA agents.

Main Results:

  • DFI management is complicated by polymicrobial infections and rising MRSA prevalence.
  • Existing anti-MRSA treatments face limitations due to resistance and adverse effects.
  • Research into new therapeutic options for MRSA in DFI is crucial.

Conclusions:

  • Effective DFI management requires robust infection control, antimicrobial stewardship, and rapid diagnostics.
  • There is a critical need for novel therapeutic strategies to address MRSA in diabetic foot infections.
  • Ongoing research into new drugs offers potential for improved DFI treatment outcomes.
Keywords:
antimicrobial resistancediabetic foot infection (DFI)methicillin-resistant Staphylococcus aureus (MRSA)multidrug-resistant infectionnewer anti-MRSA agents

More Related Videos

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus08:32

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

1.2K
Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus09:03

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

12.3K

Related Concept Videos

Muscles of the Leg that Move the Foot and Toes01:28

Muscles of the Leg that Move the Foot and Toes

The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
4.0K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.3K
Resistivity01:22

Resistivity

When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.4K
Resistance01:19

Resistance

When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
5.7K
Resistance and Conductance01:25

Resistance and Conductance

A conductor's DC resistance at a given temperature is influenced by its resistivity, length, and cross-sectional area. Resistivity is an inherent property of the conductor material, with annealed copper serving as the international standard for measurement. For instance, the resistivity of hard-drawn aluminum at 20 degrees Celsius is 61% of the standard conductivity of annealed copper.
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
495
Equivalent Resistance01:16

Equivalent Resistance

In circuit analysis, situations often arise where resistors are neither in series nor parallel configurations. To tackle such scenarios, three-terminal equivalent networks like the wye (Y) (Figure 1 (a)) or tee (T) and delta (Δ) (Figure 1 (b)) or pi (π) networks come into play. These networks offer versatile solutions and are frequently encountered in various applications, including three-phase electrical systems, electrical filters, and matching networks.
943