Robot-assisted single-port radical prostatectomy: A phase 1 clinical study

Area of Science:

• Urology
• Surgical Oncology
• Robotic Surgery

Background:

• Prostate cancer is a leading cause of cancer death in men.
• Radical prostatectomy is a common treatment for localized prostate cancer.
• Minimally invasive surgical techniques are continually being developed to improve patient outcomes.

Purpose of the Study:

• To evaluate the safety and feasibility of robot-assisted single-port radical prostatectomy (SPRP) using the da Vinci SP surgical system.
• To assess primary outcomes including conversion rates and 30-day complications.
• To analyze secondary outcomes such as operative time, blood loss, and pathological results.

Main Methods:

• A prospective phase 1 clinical study was conducted.
• Twenty prostate cancer patients underwent robot-assisted SPRP.
• Outcomes measured included operative time, blood loss, complications, hospital stay, and pathological data.

Main Results:

• No patients required conversion to a multiport approach or experienced intraoperative complications.
• The mean operative time was 208.9 minutes with a mean blood loss of 296.3 mL.
• Postoperative complications were Clavien grade I-II and resolved with conservative management.

Conclusions:

• Robot-assisted single-port radical prostatectomy with the da Vinci SP system is a safe and technically feasible procedure.
• The technique demonstrates potential for improved patient recovery and outcomes in prostate cancer treatment.
• Further research is warranted to explore long-term oncological and functional results.