Related Experiment Video
Updated: Jan 22, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Organophosphate intoxication in 2 dogs from ingestion of cattle ear tags
Vibha R Asokan1, Marie E Kerl1, Tim Evans2
1Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri.
Objective:
To describe 2 cases of organophosphate intoxication through a previously unreported method of exposure.
Case Series:
A 2-year-old intact male Australian Cattle Dog (case 1) presented with progressive muscarinic and nicotinic clinical signs, and a 3-year-old neutered male mixed breed dog (case 2) presented after known ingestion of cattle ear tags. The dog in case 1 was discovered to have ingested cattle ear tags after abdominal radiographs. Organophosphate testing of gastric contents confirmed diazinon toxicosis. The dog in case 2 was found to be eating ear tags by the owner. The tags in case 2 contained diazinon and coumaphos. The dog in case 1 was treated with gastric lavage, gastroprotectants, prokinetics, antiemetics, pralidoxime chloride, and atropine. The dog in case 2 was treated with pralidoxime chloride. Both patients received standard supportive and nursing care and recovered completely with no further concerns.
New Or Unique Information Provided:
This is a novel exposure to organophosphates that has not been reported in small animals. In dogs with relevant clinical signs and potential environmental exposure, cattle ear tag ingestion is an important differential diagnosis to consider.
Related Concept Videos
Physiology of the Gastrointestinal System I: Ingestion and Propulsion
Anatomy of the Ear
Tagging and Fusion Proteins
meta-Directing Deactivators: –NO2, –CN, –CHO, –⁠CO2R, –COR, –CO2H
2° Amines to N-Nitrosamines: Reaction with NaNO2
SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a...

