[Left ventricular ejection time in aortic valve diseases. 1. Multidimensional relationship with biometric and...

The purpose of this work is to settle biometrical and physiological factors linked to changes in ejection time in aortic valvular disease. The relationship between the various considered variables is submitted to multivariate statistical analysis, and expressed by a prediction formula. Data are provided by a series of 160 aortic patients whose examination notably includes measurement of cardiac output and of pressures in left ventricle and aorta, a cineangiography in the ascending aorta, and a search for aortic valvular calcifications with an image intensifier. Moreover, the already published results of a reference series of 200 subjects without aortic disease, are also used. Multivariate relationship of ejection time appears to be, on the whole, similar in the reference series and in the aortic series, with besides, in the latter, a significant effect of aortic "gradient" and incompetence. Consequently these two marks of aortic disease may be indirectly predicted from the residuals of the reference formula applied to aortic patients.