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Updated: Jan 22, 2026

Tuning the Acidity of Pt/ CNTs Catalysts for Hydrodeoxygenation of Diphenyl Ether
Published on: August 17, 2019
Tuning Pd-nanoparticle@MIL-101(Cr) Catalysts for Tandem Reductive Amination
Amanda E Anderson1, Christopher J Baddeley1, Paul A Wright1
1EaStCHEM School of Chemistry, University of St Andrews, Purdie Building, North Haugh, St. Andrews, Fife KY16 9ST UK.
Abstract:
The versatility of MOFs as highly porous Lewis acidic supports for precious metal nanoparticles has been exploited for one-pot tandem reductive amination catalysis. MIL-101(Cr) loaded with Pd nanoparticles ca. 3 nm in size at 0.2-1 wt% has been used to catalyse the reaction of 4'-fluoroacetophenone with benzylamine under 10 bar of H2 to give the secondary amine, 4'-fluoro-α-methyl-N-phenylmethylbenzenemethanamine. For the highest Pd loading, major hydrogenolysis of the secondary amine occurs in a second tandem reaction, but by changing the ratio of Pd to Lewis acidic Cr3+ active sites it is possible to tune the catalytic selectivity to the desired 2° amine product. An empirical kinetic analysis was performed to demonstrate this active site complementarity.
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