Related Experiment Video
Updated: Jan 22, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
Bilateral Transient Myopia with Sulfasalazine Treatment
Tal Paz1, Daniel Rappoport1,2, Assaf Hilely1
1Ophthalmology Department, Kaplan Medical Center, Rehovot, Israel.
Purpose:
Several case reports of transient drug-induced myopia have been reported, mainly due to sulfa drugs. We present a case of a sudden and significant increase in myopia associated with initiation of Sulfasalazine for long-standing ulcerative colitis in an adult Caucasian female.
Case Report:
Our patient presented to the emergency room with acute bilateral visual loss. Ocular examination was normal, except for myopia of -4 Diopters (D) in both eyes (BE). The patient was advised to stop the medication, and her vision improved within 4 days to best corrected visual acuity (BCVA) of 6/7.5 with a refractive correction of -0.75 D in her right eye (RE) and BCVA of 6/6 with a refractive correction of -0.50 D in her left eye (LE).
Conclusion:
To the best of our knowledge, this is the second reported case of transient Sulfasalazine-induced myopia.
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