Etiology and outcomes of convulsive status epilepticus in children

Muhammad Uzair1, Asif Ibrahim2, Faisal Zafar3

  • 1Dr. Muhammad Uzair MBBS, FCPS (Pediatrics), Fellow Pediatrics Neurology, Department of Pediatric Neurology, Children Hospital Lahore, Pakistan.

Insights

Acute symptomatic causes of pediatric convulsive status epilepticus are common and linked to worse outcomes. This study highlights the need for timely intervention and management strategies for better patient recovery.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Critical Care Medicine

Background:

  • Convulsive status epilepticus (CSE) is a neurological emergency in children.
  • Understanding the diverse etiologies and outcomes of CSE is crucial for effective management.

Purpose of the Study:

  • To investigate the various causes of CSE in pediatric patients.
  • To analyze the associated outcomes, including recovery, morbidity, and mortality.

Main Methods:

  • A prospective study of 73 pediatric patients presenting with CSE from January 2018 to June 2018.
  • Data collection included etiological factors and patient outcomes.
  • Statistical analysis was performed to determine significant associations.

Main Results:

  • Acute symptomatic etiology (34%) was the most frequent cause of CSE.
  • CSE was controlled within one hour in 57% of patients.
  • Mortality was 22%, with 10.9% of deaths linked to acute symptomatic causes.

Conclusions:

  • Acute symptomatic etiology is a predominant cause of pediatric CSE.
  • CSE associated with acute symptomatic causes has a poorer prognosis and higher mortality rates.
Abstract

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