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A Rare Case of Hyperhomocysteinemia-associated Thrombotic Stroke in the Pediatric Age Group

Hitanshu Dave1, Parth Dalal2, Pooja Patel3

  • 1Internal Medicine, Hackensack Meridian Health Jersey Shore University Medical Center, Neptune City, USA.

Cureus
|July 2, 2019
PubMed

Insights

Genetically inherited hyperhomocysteinemia can cause stroke in children. This case highlights a 14-year-old experiencing cerebellar and medullary infarction due to this condition, emphasizing the need for awareness.

Area of Science:

  • Neurology
  • Pediatrics
  • Genetics

Background:

  • Hyperhomocysteinemia is a known risk factor for stroke in adults.
  • Pediatric stroke associated with hyperhomocysteinemia is rarely reported in medical literature.

Observation:

  • A 14-year-old presented with dizziness and vomiting.
  • Neurologic examination revealed right-sided cerebellar signs, including ataxia.
  • Diagnostic workup confirmed bilateral cerebellar and medullary infarction.

Findings:

  • The patient was diagnosed with acute non-hemorrhagic stroke.
  • The stroke was linked to genetically inherited hyperhomocysteinemia.

Implications:

  • This case underscores the importance of considering hyperhomocysteinemia in pediatric stroke evaluations.
  • Early diagnosis and management of hyperhomocysteinemia may prevent severe neurologic events in children.
  • Highlights the need for further research into genetic causes of stroke in pediatric populations.

Keywords:
homocysteinehyperhomocysteinemianinth cranial nervepediatricstrokesyncopetenth cranial nervethrombotic strokevertigoyoung patient

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