Chronic Urticaria Associated with Helicobacter pylori

Area of Science:

• Gastroenterology
• Dermatology
• Microbiology

Background:

• Chronic pruritus and urticarial wheals can significantly impact quality of life.
• Identifying underlying causes is crucial for effective management of dermatological conditions.

Observation:

• A 31-year-old male patient experienced persistent pruritus and urticarial wheals for seven months.
• Extensive investigations revealed a positive stool antigen test for Helicobacter pylori (H. pylori).

Findings:

• The patient received a two-week course of quadruple therapy including bismuth subsalicylate, metronidazole, tetracycline, and omeprazole.
• Complete resolution of pruritus and urticarial lesions was observed within four weeks post-treatment.

Implications:

• Eradication of H. pylori may be an effective treatment strategy for chronic urticaria in some patients.
• This case highlights the importance of considering gastrointestinal infections in the differential diagnosis of refractory dermatological symptoms.