Crystallized phenol for sacral hidradenitis suppurativa

Area of Science:

• Dermatology
• Surgical Procedures

Background:

• Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition with limited effective treatments.
• Sacral HS presents unique challenges in management.

Purpose of the Study:

• To evaluate the efficacy of crystallized phenol treatment (CPT) for sacral hidradenitis suppurativa (HS).

Main Methods:

• Twenty-five patients with sacral HS underwent CPT after local anesthesia and dilation of affected openings.
• Severity was assessed using Hurley Score and HS-Physician's Global Assessment (HS-PGA).

Main Results:

• Mean follow-up was 36.8 months with an average of 3.98 CPT applications.
• Significant reductions in mean Hurley scores (2.1 to 1.2) and HS-PGA scores (3 to 0.72) were observed (p=0.01).
• Recurrences were managed with repeat CPT.

Conclusions:

• Crystallized phenol treatment demonstrates potential as an effective first-line therapy for sacral HS.