Related Experiment Video
Updated: Jan 22, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Activity of Imipenem-Relebactam and Comparator Agents against Genetically Characterized Isolates of
Matthew C Canver1,2, Michael J Satlin1,3, Lars F Westblade1,2
1New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York, USA.
Abstract:
Carbapenem-resistant Enterobacteriaceae (CRE) strains are an urgent public health threat. We evaluated the in vitro activities of 19 antimicrobial agents, including imipenem-relebactam, against (i) 106 CRE bloodstream isolates that primarily expressed Klebsiella pneumoniae carbapenemase (KPC) and (ii) 20 OXA-48-like-expressing CRE isolates. Ninety-five percent of CRE bloodstream isolates were susceptible to imipenem-relebactam. In contrast to their comparable activities against KPC-producing CRE strains, ceftazidime-avibactam was more active in vitro against OXA-48-like CRE strains than was imipenem-relebactam (90% susceptible versus 15% susceptible).
More Related Videos
Related Concept Videos
Genetics of Speciation
What is Population Genetics?
Types of Genetic Transfer Between Organisms
Resistivity
Resistance
What is Genetic Engineering?

