Two novel cyclic depsipeptides Xenematides F and G from the entomopathogenic bacterium Xenorhabdus budapestensis
Xuedong Xi1, Xingzhong Lu1, Xiaodong Zhang1
1Department of Plant Protection, Shenyang Agricultural University, 110866, Liaoning Province, China.
Abstract:
Two novel depsipeptides xenematides F and G (1, 2), were isolated from entomopathogenic Xenorhabdus budapestensis SN84 along with a known compound xenematide B. The structures of the two new molecules were elucidated using NMR, MS and Marfey's method. The xenematide G (2) contains α-aminoheptanoic acid, a non-protein amino acid that is rarely found in secondary metabolites from entomopathogenic bacteria. Xenematides F and G were tested for antibacterial activity. Xenematide G (2) exhibited moderate antibacterial activity.
Related Concept Videos
Stereoisomerism of Cyclic Compounds
Cyclic Processes And Isolated Systems
In the case of a non-isolated system, the change in the internal energy is zero only if the process is cyclic. A thermodynamic process is considered cyclic if the system undergoes a series of changes and returns to its initial state.
Consider a cyclic process that returns to its initial state, undergoing a four-step process. The heat transfer along each...
Voltammetric Techniques: Cyclic Voltammetry
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Lytic Cycle of Bacteriophages
Intracellular Signaling Cascades


