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Related Experiment Videos

Will China's H7N9 Control Strategy Continue to Be Effective?

Guo-Lin Wang1, Gregory C Gray2,3,4, Ji-Ming Chen5

  • 1State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.

Open Forum Infectious Diseases
|July 3, 2019
PubMed
Summary

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Poultry vaccination significantly reduced avian influenza A(H7N9) virus infections in birds and humans since 2017. Continued surveillance is crucial, especially for ducks, to monitor for new viral strains and pandemic risks.

Area of Science:

  • Veterinary Medicine
  • Epidemiology
  • Virology

Background:

  • The avian influenza A(H7N9) virus first emerged in China in 2013, posing a significant public health threat.
  • Interventions like live poultry market closures had limited success in controlling poultry-to-human transmission.
  • The virus continued to spread among poultry, leading to persistent human infections.

Purpose of the Study:

  • To evaluate the effectiveness of interventions, particularly poultry vaccination, in controlling avian influenza A(H7N9) virus.
  • To assess the ongoing risk of H7N9 and related avian influenza viruses.
  • To provide recommendations for future control strategies.

Main Methods:

  • Analysis of intervention effectiveness, including temporary market closures and mass poultry vaccination campaigns.
Keywords:
H7N9 virusesavian influenza virusesinterventionsvaccination

Related Experiment Videos

  • Monitoring of H7N9 virus spread in poultry populations.
  • Surveillance for novel avian influenza A virus strains, including highly pathogenic variants.

    • Main Results:

    • Temporary closure of live poultry markets reduced human infection risk but failed to halt poultry-to-poultry spread.
    • Mass vaccination of poultry commencing in September 2017 proved highly effective in preventing H7N9 infections in both poultry and humans.
    • Emergence of highly pathogenic H7N9 and H7N2 viruses in unvaccinated ducks highlights ongoing risks.

    Conclusions:

    • Poultry vaccination is a critical and effective strategy for controlling avian influenza A(H7N9) virus.
    • Continued surveillance of H7N9 variants and other avian influenza viruses in poultry, especially ducks, is essential.
    • Integrated vaccination and surveillance programs are necessary to mitigate future pandemic risks.