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Updated: Jan 22, 2026

Culturing of Human Nasal Epithelial Cells at the Air Liquid Interface
Published on: October 8, 2013
Giant basal cell carcinoma of the nasal pyramid - case report
Dănuţ Dincă1, Loredana Elena Stoica, Luminiţa Genţiana Micu
1Department of Otorhinolaryngology, Emergency County Hospital of Constanţa, Romania; ionusdilec@gmail.com; Department of Psychology, Faculty of Dental Medicine, "Ovidius" University of Constanţa, Romania; gheorgheraftu@yahoo.com.
Abstract:
Basal cell carcinoma (BCC) is a frequent form of skin cancer, which usually affects people that have been exposed to the sunlight for longer periods of time. The cells of the lower part of the epidermis are called the basal cell layer. These cells constantly divide to form new cells to replace the squamous cells that wear off the skin's surface. As these cells move up in the epidermis, they get flatter, eventually becoming squamous cells. Therefore, the BCC develops from these cells. Most BCCs have indolent behavior, with cure rates very high after low-complexity treatment. However, some lesions are very aggressive and there are only a few papers focusing on the subtype of this skin cancer known with the name ulcus rodens or giant BCC. In this study, we evaluate a case of ulcus rodens or giant BCC, subtype of the BCC skin cancer located in the area of the nasal pyramid, stage III, TxNxMx, with lymphatic and vascular invasion present.
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