Case Report: Shortest Course of Pediatric Paroxysmal Hemicrania

Ryotaro Ishii1, Ryosuke Fukazawa2, Hidesato Takezawa2

  • 1Department of Emergency & Disaster, North Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Headache
|July 3, 2019
PubMed

Insights

This case study highlights a pediatric patient with paroxysmal hemicrania (PH), a rare headache disorder. Short-term, low-dose indomethacin treatment proved effective, suggesting its potential for managing pediatric PH.

Area of Science:

  • Neurology
  • Pediatrics
  • Headache Medicine

Background:

  • Paroxysmal hemicrania (PH) is a rare primary headache disorder.
  • Pediatric cases of PH are particularly uncommon.
  • This report details the first Japanese pediatric PH case.

Observation:

  • An 11-year-old boy presented with severe, unilateral headaches lasting 2-20 minutes, occurring 20-30 times daily.
  • Associated autonomic symptoms included conjunctival injection, lacrimation, nasal congestion, eyelid edema, and ptosis.
  • The patient experienced a rapid headache resolution within two days of initiating low-dose indomethacin.

Findings:

  • The pediatric PH case presented with the shortest reported course.
  • Indomethacin at 0.9 mg/kg/day was highly effective in resolving the headache.
  • The patient remained headache-free for over a year after a brief 14-day treatment course, despite drug eruptions.

Implications:

  • Highlights the need for increased physician awareness of PH in children.
  • Suggests that low-dose, short-term indomethacin may be a viable treatment option for pediatric PH.
  • Warrants further investigation into the efficacy and safety of abbreviated indomethacin regimens for pediatric headache disorders.

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