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Case Report: Shortest Course of Pediatric Paroxysmal Hemicrania
Ryotaro Ishii1, Ryosuke Fukazawa2, Hidesato Takezawa2
1Department of Emergency & Disaster, North Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Insights
This case study highlights a pediatric patient with paroxysmal hemicrania (PH), a rare headache disorder. Short-term, low-dose indomethacin treatment proved effective, suggesting its potential for managing pediatric PH.
Area of Science:
- Neurology
- Pediatrics
- Headache Medicine
Background:
- Paroxysmal hemicrania (PH) is a rare primary headache disorder.
- Pediatric cases of PH are particularly uncommon.
- This report details the first Japanese pediatric PH case.
Observation:
- An 11-year-old boy presented with severe, unilateral headaches lasting 2-20 minutes, occurring 20-30 times daily.
- Associated autonomic symptoms included conjunctival injection, lacrimation, nasal congestion, eyelid edema, and ptosis.
- The patient experienced a rapid headache resolution within two days of initiating low-dose indomethacin.
Findings:
- The pediatric PH case presented with the shortest reported course.
- Indomethacin at 0.9 mg/kg/day was highly effective in resolving the headache.
- The patient remained headache-free for over a year after a brief 14-day treatment course, despite drug eruptions.
Implications:
- Highlights the need for increased physician awareness of PH in children.
- Suggests that low-dose, short-term indomethacin may be a viable treatment option for pediatric PH.
- Warrants further investigation into the efficacy and safety of abbreviated indomethacin regimens for pediatric headache disorders.
Abstract:
Paroxysmal hemicrania (PH) is a rare primary headache disorder, especially among children. We describe herein a case with the shortest course of pediatric PH among previously reported cases, and the first case report of Japanese pediatric PH. An 11-year-old boy was referred to our clinic by his primary care physician for a headache evaluation. He had been complaining of severe, sharp, pulsating headache for 5 days. Attacks were restricted to the left side with a duration ranging from 2 to 20 minutes, 20-30 times a day. Attacks were associated with left autonomic symptoms (conjunctival injection, lacrimation, nasal congestion, eyelid edema, and ptosis). Two days after we prescribed indomethacin at 0.9 mg/kg/day, the patient was headache free. He stopped taking indomethacin 14 days after consultation because of drug eruptions. As of the time of writing, more than 1 year later, he has experienced no recurrence of headache. This case indicates the importance of improving awareness among general doctors regarding PH in children, and of conducting further investigations about low-dose, short-term indomethacin treatment.
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