Management of kidney cancer patients: 2018 guidelines of the Italian Medical Oncology Association (AIOM)

Maria Giuseppa Vitale1, Sergio Bracarda2, Laura Cosmai3

  • 1Medical Oncology Unit, Azienda Ospedaliera Universitaria di Modena, Modena, Italy.

Tumori
|July 3, 2019
PubMed

Insights

Recent advancements in targeted therapies and immune-checkpoint inhibitors have transformed metastatic renal cell carcinoma treatment. These guidelines offer evidence-based recommendations for managing renal cell carcinoma (RCC).

Area of Science:

  • Oncology
  • Medical Guidelines

Background:

  • Metastatic renal cell carcinoma (mRCC) treatment has evolved significantly over the past 20 years.
  • New targeted therapies (VEGF and mTOR inhibitors) and immune-checkpoint inhibitors have emerged.

Purpose of the Study:

  • To provide evidence-based clinical guidelines for renal cell cancer (RCC) management.
  • To offer recommendations for healthcare professionals involved in RCC patient care.

Main Methods:

  • Development of clinical guidelines by the Italian Association of Medical Oncology (AIOM) Renal Cell Cancer (RCC) Guidelines Panel.
  • Evidence-based information synthesis for treatment recommendations.

Main Results:

  • The guidelines reflect the current, significantly changed treatment landscape for mRCC.
  • Recommendations are provided for the use of novel therapeutic agents.

Conclusions:

  • The AIOM RCC Guidelines Panel has established updated recommendations for mRCC management.
  • These guidelines aim to support oncologists, urologists, and other professionals in optimizing patient care.

Related Concept Videos

Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
227
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
219
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
185
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
322
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
258
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
409