Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spontaneity02:21

Spontaneity

28.9K
A spontaneous process is one that occurs naturally under certain conditions. A nonspontaneous process, on the other hand, will not take place unless it is “driven” by the continual input of energy from an external source. Processes have a natural tendency to occur in one direction under a given set of conditions. Water will naturally flow downhill (spontaneous process), but uphill flow (nonspontaneous process) requires outside intervention such as the use of a pump. Iron exposed to...
28.9K
Protein-protein Interfaces02:04

Protein-protein Interfaces

14.6K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.6K
Protein-Protein Interfaces02:04

Protein-Protein Interfaces

4.4K
4.4K
Protein Networks02:26

Protein Networks

4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
Protein Networks02:26

Protein Networks

2.8K
2.8K
Network Covalent Solids02:18

Network Covalent Solids

16.1K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Continuous electricity from charged total dissolved solids in wastewater using a wood-based ion-selective power generator.

Nature communications·2026
Same author

Coupling electron snorkels with biogenic FeS<sub>x</sub>-associated interfacial structures enhances anaerobic petroleum hydrocarbon degradation.

Journal of hazardous materials·2026
Same author

Split Hand/Foot Malformation with Acquired Middle Ear Cholesteatoma Secondary to Eustachian Tube Dysfunction: A Case Report and Literature Review.

International medical case reports journal·2026
Same author

Avena sativa L. boosts Lolium perenne L. growth through root exudate reprogramming under extreme high temperature.

Plant science : an international journal of experimental plant biology·2026
Same author

Water filtration using softwood membranes provides a nature-based solution for nanoplastic removal.

Communications earth & environment·2026
Same author

Clinical features of biliary atresia complicated by cytomegalovirus infection and prognostic analysis after Kasai portoenterostomy.

Journal of pediatric surgery·2026

Related Experiment Video

Updated: Jan 22, 2026

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity
07:58

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity

Published on: August 28, 2020

10.3K

Creating an Interface: Rendering a Double-Network Hydrogel Lubricious via Spontaneous Delamination.

Kaihuan Zhang1, Rok Simic1, Wenqing Yan1

  • 1Laboratory for Surface Science and Technology, Department of Materials , ETH Zurich , 8093 Zurich , Switzerland.

ACS Applied Materials & Interfaces
|July 3, 2019
PubMed
Summary

Researchers developed a novel two-step cross-linking method for creating advanced hydrogels. This technique leverages oxygen inhibition to engineer unique surface properties, resulting in highly lubricious materials for diverse applications.

Keywords:
cross-linking gradientsdelaminationhydrogelslubricious surfacesoxygen inhibition

More Related Videos

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation
07:28

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation

Published on: November 4, 2021

3.3K
Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks
09:33

Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks

Published on: March 29, 2018

10.2K

Related Experiment Videos

Last Updated: Jan 22, 2026

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity
07:58

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity

Published on: August 28, 2020

10.3K
Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation
07:28

Photodegradable Hydrogel Interfaces for Bacteria Screening, Selection, and Isolation

Published on: November 4, 2021

3.3K
Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks
09:33

Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks

Published on: March 29, 2018

10.2K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Surface Engineering

Background:

  • Hydrogels with tailored surface properties are crucial for applications in electronics, biomedical devices, and lubrication.
  • Conventional hydrogel fabrication often faces challenges with oxygen inhibition during free-radical polymerization, leading to undesirable surface defects.
  • Oxygen inhibition, typically a hindrance, can be harnessed to create controlled surface structures.

Purpose of the Study:

  • To develop a two-step cross-linking strategy for fabricating P(AAm-AMPS)/alginate double-network hydrogels with controlled surface chemistry.
  • To investigate the utilization of oxygen inhibition in air for creating unique hydrogel surface architectures.
  • To achieve independent control over surface functionality and properties compared to conventional methods.

Main Methods:

  • Fabrication of a P(AAm-AMPS)/alginate double-network hydrogel using a two-step cross-linking strategy in the presence of air.
  • Exploitation of oxygen inhibition to create a distinct surface layer.
  • Spontaneous delamination of an alginate-rich skin layer due to mechanical and osmotic instabilities.
  • Characterization of the resulting lubricious surface properties.

Main Results:

  • Successful fabrication of a double-network hydrogel with independent control over surface chemistry and functionality.
  • Formation of an alginate-rich skin layer that spontaneously delaminates.
  • Achieved a highly lubricious surface with a coefficient of friction as low as 0.02 against glass in aqueous solutions.
  • Demonstrated the potential for generalized application to develop soft functional materials.

Conclusions:

  • The proposed two-step cross-linking strategy effectively utilizes oxygen inhibition to engineer hydrogel surfaces.
  • This method allows for precise control over surface chemistry and functionality, surpassing conventional techniques.
  • The resulting delaminated surface exhibits exceptional lubricity, opening avenues for advanced lubrication applications.
  • The strategy provides a versatile platform for developing novel soft functional materials with tailored surface properties.