Related Experiment Video
Updated: Jan 22, 2026

Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells
Published on: October 20, 2015
Dissecting Prognostic From Predictive Utility: Circulating AR-V7 Biomarker Testing for Advanced Prostate Cancer
Adam Sharp1, Nuria Porta1, Maryou B K Lambros1
1Adam Sharp, MD, PhD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom; Nuria Porta, PhD; Maryou B.K. Lambros, MPhil; and Jonathan C. Welti, PhD, The Institute of Cancer Research, London, United Kingdom; Alec Paschalis, MD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom; Ganesh V. Raj, MD, PhD, The University of Texas Southwestern Medical Center, Dallas, TX; Stephen P. Plymate, MD, University of Washington; VA Puget Sound Health Care System Geriatric Research Education and Clinical Center, Seattle, WA; and Johann S. de Bono, MD, PhD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom.
No abstract available in PubMed .
Related Concept Videos
Predicting Molecular Geometry
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
Overview of Pulmonary Circulation
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
Extraction: Advanced Methods

