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Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing
Published on: July 17, 2019
A Tense Situation: Maintaining ER Homeostasis during Lipid Droplet Budding
Siti Nur Sarah Morris1, James A Olzmann2
1Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA, USA.
Abstract:
In this issue of Developmental Cell, Chorlay et al. (2019) provide evidence that asymmetric membrane surface tension determines the directionality of lipid droplet (LD) emergence. Furthermore, phospholipid synthesis "refills" the outer leaflet of the endoplasmic reticulum (ER) membrane to maintain cytosolic LD emergence and prevent disruptions to ER homeostasis.
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