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Whooping cough and unrecognised postperinatal mortality.

A Nicoll1, A Gardner

  • 1Department of Child Health, Queen's Medical Centre, Nottingham.

Archives of Disease in Childhood
|January 1, 1988
PubMed
Summary

Sudden infant death syndrome (SIDS) and respiratory infant mortality in England and Wales showed a notable increase linked to whooping cough outbreaks between 1977 and 1982. This suggests whooping cough significantly impacts infant mortality beyond its direct certified causes.

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Area of Science:

  • Pediatrics
  • Epidemiology
  • Public Health

Background:

  • Postperinatal infant mortality and sudden infant death syndrome (SIDS) are significant public health concerns.
  • Understanding trends and potential contributing factors is crucial for prevention strategies.

Purpose of the Study:

  • To examine trends in postperinatal infant mortality and SIDS in England and Wales from 1968 to 1984.
  • To investigate associations between these mortality trends and the incidence of specific infectious diseases.

Main Methods:

  • Time series analysis was employed to compare infant mortality data with infectious disease incidence.
  • Data spanned from 1968 to 1984 in England and Wales.

Main Results:

  • A significant discontinuity in infant mortality trends was observed correlating with whooping cough (pertussis) incidence between 1977 and 1982.

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  • Associations with general respiratory infections and other specific organisms were less pronounced.
  • An estimated 460 to 700 excess infant deaths were linked to whooping cough during this period.

    • Conclusions:

    • Whooping cough outbreaks appear to be associated with a substantial increase in postperinatal infant mortality and SIDS.
    • The findings suggest that the impact of whooping cough on infant mortality may be underestimated when considering only certified causes.