Related Experiment Video

Updated: Jan 22, 2026

Isolation, Cryopreservation and Culture of Human Amnion Epithelial Cells for Clinical Applications
05:31

Isolation, Cryopreservation and Culture of Human Amnion Epithelial Cells for Clinical Applications

Published on: December 21, 2014

14.4K

Development of a new reproductive tissue cryopreservation clinical service for children: the Oxford programme

K Lakhoo1,2, J Davies3, S Chakraborty4

  • 1Department of Paediatric Surgery, University of Oxford and Oxford University Hospitals, Oxford, UK. Kokila.lakhoo@nds.ox.ac.uk.

Pediatric Surgery International
|July 4, 2019
PubMed

Insights

A new fertility preservation service was developed for children at risk of infertility. This reproductive tissue cryopreservation program offers safe and effective treatment, prioritizing patient proximity to home.

Area of Science:

  • Reproductive medicine
  • Oncology
  • Paediatric healthcare

Background:

  • Children undergoing cancer treatment face risks of infertility.
  • The NHS sought to establish fertility preservation services amidst financial constraints.

Purpose of the Study:

  • To describe the development of a reproductive tissue cryopreservation service for children at high risk of infertility.
  • To outline the phased implementation within the NHS.

Main Methods:

  • A two-phase development plan was implemented.
  • Phase 1 focused on childhood cancer patients at a specific treatment center.
  • Phase 2 expanded the service across England, Wales, and Ireland, addressing resource challenges and patient accessibility.

Main Results:

  • Developed comprehensive information resources, eligibility criteria, and referral pathways.
  • Established multidisciplinary teams and a network of third-party sites.
  • Secured a dedicated theatre list and implemented a case management database, receiving positive patient feedback.

Conclusions:

  • The Oxford Reproductive Cryopreservation programme successfully provides fertility preservation to pediatric and young adult patients.
  • The program operates safely, effectively, and with a focus on patient convenience.
  • Future plans include seeking national funding for program sustainability and recognition.
Abstract

Keywords:
ChildrenCryopreservationOvaryPremature ovarian and testicular insufficiencyReproductive tissueTestisYoung adults

More Related Videos

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

10.8K
Portable Intermodal Preferential Looking IPL: Investigating Language Comprehension in Typically Developing Toddlers and Young Children with Autism10:11

Portable Intermodal Preferential Looking IPL: Investigating Language Comprehension in Typically Developing Toddlers and Young Children with Autism

Published on: December 14, 2012

19.0K

Related Concept Videos

Reproductive Cloning01:27

Reproductive Cloning

Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic...
32.6K
Overview of the Reproductive System01:31

Overview of the Reproductive System

The reproductive system generates offspring, ensuring the survival of the species. In humans, the reproductive system is complex and involves a variety of organs and hormones that work together to ensure successful reproduction.
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
5.1K
Asexual Reproduction02:38

Asexual Reproduction

Asexual reproduction allows plants to reproduce without growing flowers, attracting pollinators, or dispersing seeds. Offspring are genetically identical to the parent and produced without the fusion of male and female gametes.
37.2K
Primary Healthcare Services01:30

Primary Healthcare Services

Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
2.0K
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.9K
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.9K