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Live Vaccines Against Plasmodium Preerythrocytic Stages

Laura Mac-Daniel1, Robert Ménard2

  • 1Health Sciences Division, Burn and Shock Trauma Research Institute, Loyola University Chicago, Maywood, IL, USA.

Methods in Molecular Biology (Clifton, N.J.)
|July 4, 2019
PubMed
Summary

Live attenuated malaria vaccines targeting the preerythrocytic stage offer sterile protection. This chapter reviews rodent studies on parasite attenuation methods and human vaccination regimens for malaria elimination.

Keywords:
Genetically attenuated parasitesLive vaccineMalariaParasites attenuated by chemotherapyPreerythrocytic stagesRadiation-attenuated sporozoitesSubunit vaccine

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