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Updated: Jan 22, 2026
11:51
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
Published on: March 2, 2011
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Examining the association between grip strength and testosterone.
Hao-Tse Chiu1, Mu-Tsun Shih2, Wei-Liang Chen1,3,4
1Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital, and School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Summary
Testosterone levels are linked to greater grip strength, potentially serving as an early indicator of muscle weakness. This finding is particularly relevant for aging populations seeking to maintain physical function.
Area of Science:
- Endocrinology
- Gerontology
- Sports Medicine
Background:
- Skeletal muscle plays a vital role in protein storage and overall physical function.
- Muscle strength decline often precedes muscle mass reduction, especially during aging.
- Identifying early biomarkers for muscle weakness is crucial for timely intervention.
Purpose of the Study:
- To investigate the association between serum testosterone levels and handgrip strength.
- To explore testosterone as a potential early biomarker for detecting age-related muscle weakness.
Main Methods:
- Quartile-based analysis of handgrip power.
- Linear regression to assess the relationship between handgrip power and testosterone.
- Logistic regression models to analyze the longitudinal correlation between testosterone and low muscle strength.
Main Results:
- Serum testosterone levels showed a significant positive correlation with grip strength (p < .001).
- Higher testosterone levels were consistently associated with lower prevalence of muscle weakness (p < .001).
- The association between testosterone and grip strength was stronger in non-obese individuals compared to obese individuals.
Conclusions:
- Testosterone levels are significantly related to greater grip strength.
- Testosterone may serve as a valuable biomarker for assessing muscle strength and function, particularly in aging.
- Maintaining adequate testosterone levels could be important for preserving muscle strength throughout life.
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