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Ozonated Oils and Cutaneous Wound Healing.

Yunsook Lim1, Heaji Lee1, Brittany Woodby2

  • 1Department of Food and Nutrition, Kyung Hee University, Seoul 02447, Korea.

Current Pharmaceutical Design
|July 4, 2019
PubMed
Summary

Ozonated oils, derived from vegetable matrices, show promise for enhancing wound healing. Their antimicrobial properties may accelerate the closure of chronic wounds, particularly in conditions like diabetes.

Keywords:
Cutaneous wound healingROSinflammationozonated oilperoxidationtopical application.

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Area of Science:

  • Dermatology
  • Biomedical Engineering
  • Pharmacology

Background:

  • Wound healing is a complex biological process crucial for tissue regeneration.
  • Chronic wounds, often seen in diabetes, present significant challenges due to delayed closure.
  • Novel therapeutic strategies are continuously explored to improve wound repair.

Purpose of the Study:

  • To review the current applications of topical ozonated oils in cutaneous wound management.
  • To highlight the significance of the ozonation degree in ozonated oils for therapeutic efficacy.
  • To explore the potential of ozonated oils in addressing delayed wound healing.

Main Methods:

  • Literature review of studies investigating topical ozonated oil for wound healing.
  • Analysis of research focusing on the antimicrobial and regenerative properties of ozonated oils.
  • Emphasis on the correlation between ozonation degree and therapeutic outcomes.

Main Results:

  • Ozonated oils demonstrate significant bactericidal, antiviral, and antifungal activities.
  • Topical application of ozonated oils has shown positive effects on accelerating wound closure.
  • The degree of ozonation is a critical factor influencing the efficacy of ozonated oils in wound treatment.

Conclusions:

  • Ozonated oils represent a promising therapeutic agent for topical application in cutaneous wound care.
  • Their multifaceted antimicrobial properties contribute to improved wound healing, especially in chronic conditions.
  • Further research into optimizing ozonation levels is warranted to maximize therapeutic benefits.