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Updated: Jan 22, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
[Treatment of obsessive-compulsive disorder in children and adolescents]
David R M A Højgaard1, Judith B Nissen, Katja A Hybel
1davmar@rm.dk.
Abstract:
The knowledge of obsessive-compulsive disorder (OCD) and its treatment has advanced in the latest years and is summarised in this review. Child and adolescent OCD is a chronic condition, and if it is left untreated, it often continues into adulthood with debilitating effect on the quality of life. Cognitive-behavioural therapy (CBT) is the recommended first-line treatment for children and adolescents, and continued CBT or selective serotonin reuptake inhibitor treatment can be effectively given to non-responders to initial CBT. There is also emerging evidence supporting the long-term effect of CBT in this group of patients, and new variations of CBT are being investigated.
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